What happens when IBS, FODMAPs, and bacteria walk into a large intestine ? … Fermentation, or does it?

If you suffer from IBS, you may be interested in a study from Lovinsenberg Diakonale Hospital that may reveal another layer of knowledge as to what’s different between the digestion of an IBS gut and a healthy gut.

It’s already known that FODMAP carbohydrates are a trigger for many IBS sufferers and that following restriction diets to determine an individual’s persons triggers can help provide relief from the poor digestion of FODMAPs; those being gas, bloating, pain and abdominal discomfort.

This 2015 study focuses on the large intestine and the fermentation of FODMAPs that “should” take place by millions of gut bacteria feeding on dietary nutrients, breaking down the carbohydrates for their own energy, and releasing beneficial short chain fatty acids (SCFAs). The study in question used blood sample levels of SCFAs as an indicator of whether fermentation of a FODMAP (lactulose) was taking place in the colon or not.

For IBS sufferers it was not.

This reveals some potentially interesting information that the large intestine of IBS sufferers does not do the job in the usual way. For the healthy gut group, levels of SCFAs in the blood increased as fermentation took place in the large intestine, however the IBS group had even lower levels of SCFAs than before the experiment began…

Now, this was a small sample of individuals – 20 healthy and 22 with IBS, however the result was very clear dividing the two groups. The complete answer is still to be discovered, yet the researchers have proposed that fermentation in people living with IBS may be displaced and occur predominantly further down the colon and this is consistent with other studies that found higher levels of SCFAs in IBS subject faeces.

This may be related to rates of digestion, a digestive reflex or a shift in the location of the bacteria themselves, however it is clear that “rapid digestion” of these FODMAP carbohydrates in the hindgut is not an advantage, and the hindgut is generally the location of inflammation responses. In fact, isolated and rapid fermenting FODMAP fibre supplements may encourage this displacement of fermentation – effectively promoting dysbiosis.

So, what can I do with this information today?

This is very early research for a recommendation, however all signs point to the benefits of hindgut stimulation and supplying the entire colon with complex prebiotics that bring the fermentation & gas production rates down to a uniform and a more “IBS” comfortable level.

Appropriately, there is only one product “Kfibre” that is Low FODMAP, gluten free, high in insoluble fibre, and complex prebiotics that results in uniform fermentation in the entire colon, influencing the beneficial gut microbiota and delivering SCFAs (especially butyrate) to nourish the hindgut. All these benefits without the undesirable symptoms.

While you wait for the research to tell you why hindgut stimulating fibres work, you and your large intestine could already be enjoying the benefits so many others have already found when they tried Kfibre.


By HFS Tech Team